Hera’s gene editing technology is perfect for a wide range of applications, including in vivo gene expression or modifications, stable cell lines, and other complex gene editing strategies. Order gene editing reagents or inquire about Hera’s custom reagent design services.
Demonstrated in hundreds of peer-reviewed publications, the piggyBac transposon mediates efficient stable genomic transgene insertion. Use your preferred transfection method to deliver a piggyBac transposon containing your gene(s) of interest along with the piggyBac transposase as DNA or mRNA.
A limited-use research license is required to evaluate the piggyBac and Cas-CLOVER technology. For end-user license information, click here.
Shop Gene Editing Reagents
PIGGYBAC REAGENTS & SERVICES
piggyBac Starter Kit
OTS REAGENT(s) | CATALOG # | SHORT DESCRIPTION | AMOUNT | MAP | LICENSE FEE | |
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piggyBac REAGENTS, SERVICES & LICENSE | SPB-E12 |
The piggyBac starter kit includes the SPB-012 transposon with GFP/Puro expression and
SPB-100 piggyBac mRNA. |
10ug DNA
25 ug RNA |
Map Sequence |
$899.00 | Request a Quote |
TRANSPOSONS
OTS REAGENT | CATALOG # | SHORT DESCRIPTION | AMOUNT | MAP | LICENSE FEE | |
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piggyBac REAGENTS, SERVICES & LICENSE | SPB-007 |
Empty piggyBac transposon base vector with multiple cloning site (MSC)
|
10ug | Map Sequence |
$980.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-012 |
piggyBac transposon containing a CMV promoter-MCS-SV40PolyA for cloning gene of interest and a GFP-Puro selection cassette.
|
10ug | Map Sequence |
$980.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-013 |
piggyBac transposon containing a CAG promoter-MCS-SV40PolyA for cloning gene of interest and a GFP-Puro selection cassette.
|
10ug | Map Sequence |
$980.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-014 |
piggyBac transposon containing a PGK promoter-MCS-SV40PolyA for cloning gene of interest and a GFP-Puro selection cassette.
|
10ug | Map Sequence |
$980.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-015 |
piggyBac transposon containing an Ef1a promoter-MCS-SV40PolyA for cloning gene of interest and a GFP-Puro selection cassette.
|
10ug | Map Sequence |
$980.00 | Request a Quote |
TRANSPOSASES
OTS REAGENT | CATALOG # | SHORT DESCRIPTION | AMOUNT | MAP | LICENSE FEE | |
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piggyBac REAGENTS, SERVICES & LICENSE | SPB-110 |
Improved super piggyBac transposase (sPBo) mRNA
|
10ug | – | $455.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-100 |
Improved super piggyBac transposase (sPBo) mRNA
|
25ug | – | $990.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-D10 |
Improved super piggyBac transposase (sPBo) DNA
|
10ug | View Map | $535.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-D25 |
Improved super piggyBac transposase (sPBo) DNA
|
25ug | View Map | $1,330.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-002 |
Excision-only piggyBac transposase DNA
|
25ug | View Map | $1,330.00 | Request a Quote |
piggyBac REAGENTS, SERVICES & LICENSE | SPB-200 |
Improved super piggyBac transposase (sPBo) mRNA
Commercial Grade for applications that require a CoA and TSE/BSE Statement
|
25ug | – | $1,400.00 | Request a Quote |
All reagents are provided at a 1 ug/ul concentration per vial. Shipping for RNA reagents will be on dry ice (US) or LN2 cryoport (International). Shipping for DNA reagents will be ambient temperature or on ice.
Transposases are designed for direct use and cannot be propagated. Inquire for bulk ordering or quality reports or documentation.
*The transfer of reagents is subject to a limited use research license pursuant to the terms and conditions. If use of the reagents beyond these terms and conditions is desired, please contact Hera at services@herabiolabs.com for technology licensing opportunities.
CAS-CLOVER NUCLEASES THE CLEAN ALTERNATIVE TO CRISPR/CAS9
Our high-precision dimeric Cas-CLOVER gene editing system is supported by clear issued patents and combines high efficiency with undetectable off-target activity. Transfect the Cas-CLOVER mRNA with a pair of gRNAs for targeted nuclease cutting.
We offer commercial and research licenses as well as proof of concept services for this technology in drug discovery & early development.
OTS REAGENT | CATALOG # | SHORT DESCRIPTION | AMOUNT | License Fee | |
---|---|---|---|---|---|
Cas-CLOVER | CCL-100 |
Cas-CLOVER mRNA
|
25ug | $950.00 | Request a Quote |
Cas-CLOVER | CCL-200 |
Cas-CLOVER custom gRNA pair (including design service)
|
50 ug/each | $750.00 | Request a Quote |
FOOTPRINT FREE GENE EDITING® KITS
Footprint-Free Gene Editing combines piggyBac and Cas-CLOVER to allow for selection of gene editing events without leaving scarring sequences behind allowing for complex edits in even the most difficult cell lines. Our custom gene editing kits includes everything you need for targeted knock-ins. Or select one of our Multivector backbones and design your own project.
OTS REAGENT | CATALOG # | SHORT DESCRIPTION | AMOUNT | MAP | PRICE | |
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FOOTPRINT-FREE GENE EDITING KITS | SGK – 010 |
Custom Footprint-Free Gene Editing Kit (SGK-00X with custom HR arms, CCL-100, CCL-200, and SPB-002)
|
– | $5,500.00 | Request a Quote | |
FOOTPRINT-FREE GENE EDITING KITS | SGK – 001 |
Empty Multivector containing GFP and Puromycin selection cassette driven by a CMV promoter (MV-CMV-GFP-Puro).
|
– | View Map | $1,399.00 | Request a Quote |
FOOTPRINT-FREE GENE EDITING KITS | SGK – 002 |
Empty Multivector containing GFP and Puromycin selection cassette driven by a PGK promoter (MV-PGK-GFP-Puro).
|
– | View Map | $1,399.00 | Request a Quote |
FOOTPRINT-FREE GENE EDITING KITS | SGK – 004 |
Empty Multivector containing Neomycin and Thymidine Kinase selection cassette driven by a PGK promoter (MV-PGKNeo-TK).
|
– | View Map | $1,399.00 | Request a Quote |
FOOTPRINT-FREE GENE EDITING KITS | SGK – 005 |
Empty Multivector containing Puromycin and Thymidine Kinase selection cassette driven by a PGK promoter (MV-PGKPuro-TK).
|
– | View Map | $1,399.00 | Request a Quote |
FOOTPRINT-FREE GENE EDITING KITS | SGK – 006 |
Empty Multivector containing Hygromycin and Thymidine Kinase selection cassette driven by a PGK promoter (MV-PGKHygro-TK).
|
– | View Map | $1,399.00 | Request a Quote |
FOOTPRINT-FREE GENE EDITING KITS | SGK – 007 |
Empty Multivector containing Puromycin and Thymidine Kinase selection cassette driven by an EF1α promoter (MVEF1α-Puro-TK).
|
– | View Map | $1,399.00 | Request a Quote |
SAFE HARBOR SITE REAGENTS & KITS
AAVS1 donor vector and AAVS1-specific Cas-CLOVER nucleases for safe-harbor knock-in human cell lines. Simply clone in your gene of interest (GOI) into the donor vector and transfect along with the Cas-CLOVER gRNAs and Cas-CLOVER mRNA. Alternative nucleases are also suitable (Cas9, TAL-CLOVER, etc.) for use with the donor vector.
OTS REAGENT | CATALOG # | SHORT DESCRIPTION | AMOUNT | MAP | PRICE | |
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SAFE HARBOR AAVS1 REAGENTS & KITS | KSH-001 |
AAVS1 GFP-Puro vector with Cas-CLOVER
|
10ug | $1,450.00 | Request a Quote | |
SAFE HARBOR AAVS1 REAGENTS & KITS | KSH-003 |
AAVS1 Puro-TK-SH vector with Cas-CLOVER
|
10ug | $1,450.00 | Request a Quote | |
SAFE HARBOR AAVS1 REAGENTS & KITS | KSH-005 |
AAVS1 MCS SH vector with Cas-CLOVER
|
10ug | $1,450.00 | Request a Quote |
All reagents are provided at a 1 ug/ul concentration per vial. Shipping for RNA reagents will be on dry ice (US) or LN2 cryoport (International). Shipping for DNA reagents will be at ambient temperature or on ice.
Cell Line Engineering Services
Our cell-line engineering team can provide any modification including knock-in, knockout, and stable transgenic cell lines. We have years of experience handling the toughest projects with our piggyBac and Cas-CLOVER products and offer highly flexible, milestone-based services.
Animal Model Creation Services
We develop custom genetically modified mouse and rat strains using our piggyBac and Cas-CLOVER technology. Seamless transitioning through phenotyping, characterization, and CRO services by a highly trained in-vivo team significantly reduces the timeline to data.