Resource Hub

The CHOlympian Platform™ Combines Transposase-Mediated Stable Integration and Cas-CLOVER Host Modification to Deliver Highly Productive CHO Cell Lines for Biotherapeutic Manufacturing

A murine model for chronic liver-specific oligonucleotide efficacy testing

Genetically Immortalized Cells: Unlocking the Potential for Scalable Cultured Meat Production

Immortalized cells for cultured meat and seafood cell line engineering can be achieved with the piggyBac transposon technology.

Addressing the limitations of chemotherapeutic drug delivery with engineered protein polymers

The standard care of treatment for many types of cancer and infectious diseases around the world is currently chemotherapy. However, chemotherapies are widely known to be linked to severe toxicity and resistance that develop mostly due to non-specificity, leading to overall disease progression.

Cas-CLOVER achieves targeted knock-ins in induced pluripotent stem cell lines

Our better than CRISPR dimeric genome editing mechanism shines in this cell line genetic engineering use case.

Cell Line Development

Stable Cell Line Development with piggyBac

Achieve stable cell line development with piggyBac. Read our datasheet to learn more about this gene editing technology for therapeutics development. Reach out to us on how to start accelerate your research.

Discovery To Efficacy With The Experts: Pre-clinical CRO Services At Hera BioLabs

Hera provides drug efficacy studies in a variety of in vivo models, including multiple immunodeficient mouse strains and our SRG OncoRat®. Contact us to learn more.

piggyBac Case Study: Generating Full-length NKR-P1 Transfectants

Discover how piggyBac played a critical role in helping researchers build a comprehensive model of NKR-P1-LLT1 interactions to better understand how they function in immune-related diseases and cancer.

Cell Line Development

Hera Biolabs's Cas-CLOVER gene editing platform is ideal for CLD. It is easier to use than CRISPR with flexible and clear commercial terms. Send your CLD project to us to accelerate it and unburden your team.

PiggyBac Applications: Beyond Stable Cell Lines

Rapid Creation of Bioluminescent Cell Lines for Orthotopic and Metastatic Rodent Oncology Studies

In vivo bioluminescent imaging in the SRGTM OncoRat® provides an ideal platform for de-risking your pipeline and developing life-saving pharmacotherapies.

In Vivo Gene Delivery Using piggyBac With Hydrodynamic Tail Vein Injection

Overview and data describing how mutant human KRAS cell lines are highly compatible with our SRG OncoRat animal research model

In Vivo Gene Delivery Using piggyBac With Hydrodynamic Tail Vein Injection

The Potential Of piggyBac Technology In The Rapid Determination Of Ebolavirus Infectivity In Clinical Samples

In this article, we review a recent study regarding the effective use of piggyBac in creating novel cell lines capable of efficiently detecting live ebolavirus.

HepG2-CYP™ Cell Panel

Effect of Transfecting HepG2 with Human CYP Enzymes on Chemical Toxicity

Gene Editing With piggyBac: Creating A Curative Treatment For Beta-Thalassemia

Genetic Engineering Can Soon Lead To Lifelong Cures For Diseases That Were Previously Incurable - And ß-thalassemia Is The Perfect Example.

Breakthroughs In Gene Editing Allow For The Creation Of Superior Preclinical Oncology Models

Hera Biolabs has used its proprietary gene editing technologies to develop ideal rat models for use in pre-clinical oncology research by oncology CROs.

Bacterial Carriers Offer New Hope In The Treatment Of Glioblastoma

The bacterial carrier most definitely opens the door for the creation of some highly targeted therapies that could effectively suppress GBM tumor growth.

Transposon Mutagenesis Helps Identify Genes Mediating Drug Resistance In The Treatment Of CLL

PiggyBac transposon mutagenesis screens have the ability to help lead the way when it comes to identifying genes that mediate patient sensitivity to specific drug therapies.

HIV-1 Gene Therapies Considered: RNAi Versus CRISPR-Cas

As additional in vivo testing in humanized rodent models continues, researchers will develop efficient and safer therapeutic strategies designed to suppress the replication of HIV-1.

Humanized MDCK Cells – Case Study

Faster & cleaner transporter assays with cPgp/cBcrp double knockout MDCKII cell line, MDCKII-BP-null™ cells, and “humanized” cell lines stably expressing ABCB1 (MDR1) gene encoding hPGP and ABCG2 gene encoding hBCRP

piggyBac Creates Human SIRPA BAC Transgenic Rat Models

Overview of obtaining human SIRPA BAC transgenic rat models for preclinical research using piggyBac transposase/transposon gene editing.

Hera BioLabs In Genetic Engineering News

Hera BioLabs and our VP of Research and Development Tseten Yeshi was featured this week in the Genetic Engineering News (GEN) article titled Humanizing Animal Models for Immuno-oncology.

Advancements In Stem Cell-Based Therapies For Malignant Brain Tumors

MSCs, particularly human adipose-derived mesenchymal stem cells (hAMSCs), have great potential as brain tumor-targeting carriers of drug therapies.