Chimeric Humanized Mouse Models: Understanding Human And Mouse Cell Interactions
Humanized liver mouse models are increasingly being used in preclinical [...]
Transposon Mutagenesis Helps Identify Genes Mediating Drug Resistance In The Treatment Of CLL
First time treatment of Chronic Lymphocratic Leukemia (CLL) generally requires [...]
PDX Models of Lung Cancer Closely Mimic Characteristics Of Patient Primary Tumors
Despite ongoing research, lung cancers have remained among the most [...]
Rat Provides A More Robust & Convenient Animal Infection Model For Hepatitis E Virus
Hepatitis E virus (HEV) is estimated to cause more than 56 thousand deaths each year, and although most infections remain asymptomatic, HEV is still considered one of the most common causes of acute viral hepatitis and is an ongoing concern for immunosuppressed transplant patients.
Orthotopic vs. Subcutaneous Xenograft Models of Human Cancer
Orthotopic vs. Subcutaneous Xenograft Models of Human Cancer Subcutaneously implanted [...]
HIV-1 Gene Therapies Considered: RNAi Versus CRISPR-Cas
Though human immunodeficiency virus type 1 (HIV-1) can now be [...]
Transgenic Rats As Research Models Boast Significant Benefits
Transgenic Rats as Research Models Boast Significant Benefits over Mouse [...]
Humanized Mouse Xenograft Models: The Best Of Both Worlds
Xenograft rodent models and cultured cells have long been used [...]
Xenograft Rat Models Give Hope To New Therapeutic Treatments For Leukemia
Mutations in DNA methyltransferase 3A (DNMT3A) are common in acute [...]
Humanized MDCK Cells – Case Study
Creating Humanized MDCK Cell Lines for Transporter Assays [...]