Humanized Mouse Models Advance Immunotherapeutic Strategies In Treatment Of Type 1 Diabetes
A relatively common autoimmune disease, Type 1 Diabetes (T1D) is [...]
Humanized Mice Allow For Better Understanding Of Interactions Between VACV & Immune System
Cancer is responsible for approximately 8 million deaths worldwide, with [...]
Humanized Mouse Model Allows For Study Of Immune Response To Decellularized ECM Biomaterials
Humanized rodent models have been used extensively for studying autoimmune [...]
Early Discovery In Rats And Humanized Rodents
Do you have a compound and want a quick and cost effective in vivo evaluation? We offer a range of preliminary in vivo capabilities as well as the ability to screen compounds in both traditional animal rodent models, such as Sprague-Dawley rats and genetically engineered models (custom services & in vivo liver gene delivery available) including “humanized” liver rodent models, which are immunodeficient animals in which the native liver has been ablated and then engrafted with human hepatocytes, which proliferate to restore the functioning liver.
HIS Mice Provide New Preclinical Model For Human Skin Immunity
Despite the convenience and appeal of oral therapies, the reality [...]
What’s Old Is New Again: Chemical Carcinogenesis Models Of Cancer
Early cancer research focused primarily on chemical carcinogenesis in rat [...]
New Mouse Model Enables In Vivo Assessment Of Immunotherapies For Treating CGD
Chronic granulomatous disease (CGD) is best described as an immune [...]
Patient Derived Xenografts Possess Significant Advantages In The Study Of Urological Tumors
The more researchers learn about various cancers, the complexity of [...]
Bacterial Carriers Offer New Hope In The Treatment Of Glioblastoma
Unlike many cancers, which have seen a tremendous increase in [...]
Rat Models Provide Superior Insights Into Mutagenic/Carcinogenic Responses In Humans
Although in-vitro bacterial mutation assays and murine models have long [...]